Description

Quinoline, 3-[(Trimethylsilyl)Methyl]- (9Ci) is a specialized organosilicon derivative of the quinoline heterocycle, serving as a valuable synthon in advanced organic synthesis. This compound matters for its role as a versatile building block, enabling the introduction of both a quinoline moiety and a reactive trimethylsilylmethyl group into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific activity profiles.
• Ligand Precursor: Serves as a starting material for the preparation of specialized nitrogen-containing ligands used in catalysis.
• Material Science Research: Employed in the development of organic semiconductors, light-emitting materials, and advanced polymers.
• Cross-Coupling Reactions: The functional groups present make it suitable for use in palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Academic & Industrial R&D: A critical reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	Quinoline, 3-[(Trimethylsilyl)Methyl]- (9Ci)
CAS No.	65094-36-2
Molecular Formula	C₁₃H₁₉NSi
Molecular Weight	217.38 g/mol
Synonyms	3-(Trimethylsilylmethyl)quinoline; (3-Quinolinylmethyl)trimethylsilane; Trimethyl(3-quinolinylmethyl)silane; Quinoline, 3-[(trimethylsilyl)methyl]-; 3-((Trimethylsilyl)methyl)quinoline; 3-Quinolinemethanol, trimethylsilyl ether; TMSM-Quinoline
EINECS	Contact for details

Quality Control

Our Quinoline, 3-[(Trimethylsilyl)Methyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.