Description

Diethyl Bromodifluoromethanephosphonate is a specialized organophosphorus compound that serves as a versatile reagent for the introduction of the bromodifluoromethyl group. This compound is particularly valued for its role in the synthesis of fluorinated analogs of biologically active molecules, which are crucial in modern pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex, fluorine-containing target molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Synthesis: Used in the production of novel herbicides, pesticides, and fungicides with enhanced activity and environmental stability.
• Material Science: Employed in the creation of fluorinated monomers and polymers for specialty coatings and advanced materials.
• Medicinal Chemistry: A critical reagent for lead optimization and structure-activity relationship (SAR) studies to improve metabolic stability and bioavailability.
• Chemical Research: Facilitates the synthesis of complex organofluorine compounds in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Used to prepare fluorinated phosphonate ligands for catalytic applications.

Basic Information

Product Name	Diethyl Bromodifluoromethanephosphonate
CAS No.	65094-22-6
Molecular Formula	C5H10BrF2O3P
Molecular Weight	267.01 g/mol
Synonyms	Diethyl (bromodifluoromethyl)phosphonate; Bromodifluoromethylphosphonic Acid Diethyl Ester; (Bromodifluoromethyl)phosphonic Acid Diethyl Ester; Diethyl Bromodifluoromethylphosphonate; Phosphonic Acid, (Bromodifluoromethyl)-, Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl Bromodifluoromethanephosphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.