Description

3-[3-[Bis(2-Chloroethyl)Amino]Phenoxy]Propanoic Acid is a specialized nitrogen mustard derivative with a carboxylic acid functional group. This bifunctional structure makes it a valuable chemical intermediate for the synthesis of more complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily sought by research institutions and fine chemical manufacturers engaged in developing targeted therapies and advanced chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential anticancer agents and other nitrogen mustard-based therapeutics.
• Bioconjugation Agent: Used to create antibody-drug conjugates (ADCs) or other targeted drug delivery systems by linking cytotoxic payloads to targeting molecules.
• Research Chemical: Employed in academic and industrial laboratories for studying alkylating agent mechanisms and structure-activity relationships (SAR).
• Linker Molecule Synthesis: Serves as a precursor for synthesizing cleavable or non-cleavable linkers used in prodrug design and bioconjugation chemistry.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex organic molecules for various life science applications.

Basic Information

Product Name	3-[3-[Bis(2-Chloroethyl)Amino]Phenoxy]Propanoic Acid
CAS No.	64977-02-2
Molecular Formula	C₁₅H₂₁Cl₂NO₃
Molecular Weight	334.24 g/mol
Synonyms	3-[3-[Bis(2-chloroethyl)amino]phenoxy]propanoic acid; 3-[3-[Bis(2-chloroethyl)amino]phenoxy]propionic acid; NSC 382198; 3-(3-(Bis(2-chloroethyl)amino)phenoxy)propanoic acid; Phenoxypropanoic acid nitrogen mustard derivative; Carboxyalkylphenoxy nitrogen mustard
EINECS	Contact for details

Quality Control

Our 3-[3-[Bis(2-Chloroethyl)Amino]Phenoxy]Propanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.