Description

3-[4-(Dimethylaminomethyl)Phenyl]-4-Methyl-7-Phenyl-9-Oxa-4,8-Diazabicyclo[4.3.0]Nona-2,7,10-Trien-5-One is a complex heterocyclic organic compound with a bicyclic structure, serving as a valuable advanced pharmaceutical intermediate and key building block in synthetic organic chemistry. Its unique molecular architecture makes it critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This high-purity compound is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Process Chemistry Development: Serves as a critical intermediate for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final synthetic steps for producing target drug molecules, requiring stringent purity controls.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Industrial R&D: Employed in research exploring new heterocyclic chemistry, reaction methodologies, and material science applications.

Basic Information

Product Name	3-[4-(Dimethylaminomethyl)Phenyl]-4-Methyl-7-Phenyl-9-Oxa-4,8-Diazabicyclo[4.3.0]Nona-2,7,10-Trien-5-One
CAS No.	64769-68-2
Molecular Formula	C22H23N3O2
Molecular Weight	361.44 g/mol
Synonyms	9-Oxa-4,8-diazabicyclo[4.3.0]nona-2,7,10-trien-5-one, 3-[4-(dimethylaminomethyl)phenyl]-4-methyl-7-phenyl-; 4,8-Diazabicyclo[4.3.0]nona-2,7,10-trien-5-one, 9-oxa-3-[4-(dimethylaminomethyl)phenyl]-4-methyl-7-phenyl-; Bicyclic lactam intermediate 64769-68-2; DMAP-Phenyl-Oxadiazabicyclononatrienone; (Dimethylaminomethyl)phenyl-methyl-phenyl-oxadiazabicyclononatrienone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up processes. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each batch, documenting purity, identity, and impurity profiles. We support development under quality guidelines relevant to pharmaceutical intermediates, and specifications can be aligned with customer requirements for GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.