Description

(3R,4'R,5S)-5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-Octahydro-4'α-Hydroxy-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is a complex, high-purity spirocyclic furan derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create molecules with specific stereochemical configurations and biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of potential drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Research: Used as a building block for developing new pesticides or herbicides with enhanced efficacy and selectivity.
• Asymmetric Catalysis: Employed as a ligand or a substrate in catalytic reactions to induce stereoselectivity in the formation of new chiral centers.
• Material Science Research: Investigated for the synthesis of novel organic frameworks or polymers with unique optical or electronic properties.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in university and CRO laboratories.
• Fine Chemical Synthesis: Used in the production of complex fragrance or flavor ingredients where specific stereochemistry is required for olfactory or taste profiles.

Basic Information

Item	Details
Product Name	(3R,4'R,5S)-5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-Octahydro-4'α-Hydroxy-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione
CAS No.	64756-05-4
Molecular Formula	C19H20O5
Molecular Weight	328.36 g/mol
Synonyms	5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-octahydro-4'α-hydroxy-7'α-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione; Spiro[naphtho[1,8-bc]furan-6(6H),3'-[2H]furan]-2,2'(4'H)-dione derivative; CAS 64756-05-4; Octahydro spirofuran naphthofuran dione; (3R,4'R,5S)- isomer of the spiro compound; Chiral furan-naphthofuran spiro compound
EINECS	Contact for details

Quality Control

Our production of (3R,4'R,5S)-5-(3-Furyl)-3',4,5,5',5'Aβ,7',8',8'Aα-Octahydro-4'α-Hydroxy-7'α-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.