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.Alpha.-D-Glucopyranose, 1,2-o-(1-Methoxyethylidene)-, Triacetate, (R)- CAS NO 64727-26-0


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CAS No.:64727-26-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

.Alpha.-D-Glucopyranose, 1,2-o-(1-Methoxyethylidene)-, Triacetate, (R)- is a high-purity, chiral carbohydrate derivative used as a critical synthetic intermediate. This compound matters for its role in the stereoselective synthesis of complex molecules, offering a protected and activated glucose scaffold. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals where precise stereochemistry is paramount.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
  • Chiral Synthesis: Serves as a versatile chiral pool starting material or auxiliary for asymmetric synthesis in medicinal chemistry.
  • Glycochemistry Research: Used in academic and industrial labs to study glycosylation reactions and synthesize complex oligosaccharides.
  • Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
  • Bioconjugate Chemistry: Potential use in the preparation of labeled sugars or carbohydrate-protein conjugates for diagnostic applications.

Basic Information

Product Name .Alpha.-D-Glucopyranose, 1,2-o-(1-Methoxyethylidene)-, Triacetate, (R)-
CAS No. 64727-26-0
Molecular Formula C₁₅H₂₂O₁₀
Molecular Weight 362.33 g/mol
Synonyms (R)-1,2-O-(1-Methoxyethylidene)-α-D-glucopyranose Triacetate; 1,2-O-(1-Methoxyethylidene)-α-D-glucopyranose 3,4,6-Triacetate; α-D-Glucopyranose, 1,2-O-(1-methoxyethylidene)-, 3,4,6-triacetate, (R)-; (R)-3,4,6-Tri-O-acetyl-1,2-O-(1-methoxyethylidene)-α-D-glucopyranose; 3,4,6-Tri-O-acetyl-1,2-O-(1-methoxyethylidene)-α-D-glucopyranose; Protected D-Glucose Derivative
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Quality Control

Our .Alpha.-D-Glucopyranose, 1,2-o-(1-Methoxyethylidene)-, Triacetate, (R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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