Description

Oxonol Vi CAS NO 64724-75-0 is a specialized oxonol dye belonging to the polymethine cyanine class, widely recognized for its potent fluorescence quenching and membrane potential-sensing capabilities. This compound is critical for researchers and manufacturers requiring precise optical probes for biophysical and biochemical assays. It is primarily utilized in life sciences, diagnostics, and advanced materials research for applications such as membrane potential imaging, fluorescence microscopy, and as a component in sensor technologies.

Application

• Membrane Potential Sensing: Acts as a fast-response potentiometric probe for monitoring transmembrane potential changes in cells, organelles, and artificial membranes.
• Fluorescence Quenching & Microscopy: Used in fluorescence resonance energy transfer (FRET) assays and as a quencher in various fluorescence-based detection systems for high-resolution cellular imaging.
• Biochemical Research Reagent: Serves as a key component in assay kits for studying ion channel activity, mitochondrial function, and cellular physiology.
• Diagnostic Assay Development: Employed in the formulation of diagnostic sensors and test strips for clinical and research applications.
• Photodynamic & Electro-Optical Materials: Investigated for use in the development of advanced materials for photodynamic therapy, organic electronics, and light-harvesting systems.

Basic Information

Product Name	Oxonol Vi
CAS No.	64724-75-0
Molecular Formula	C29H31N2O6S3-
Molecular Weight	599.75 g/mol (Anion)
Synonyms	Bis-(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxonol; Oxonol VI; Oxonol V; Potential-sensitive oxonol dye VI; Fluorescent oxonol dye; Bis(3-propyl-4-isoxazolyl)pentamethine oxonol; DiBAC4(5) analog; Membrane potential indicator VI
EINECS	Contact for details

Quality Control

Our Oxonol Vi is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/fluorescence profiles, and other relevant specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light, which can degrade the compound.

Specification

Item	Specification
Appearance	Dark green to black crystalline powder
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Absorbance (λmax in Methanol)	590 - 610 nm
Extinction Coefficient (ε)	Contact for details
Loss on Drying	≤ 2.0 %
Residue on Ignition (Sulfated Ash)	≤ 0.5 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.