Description

Ethyl 5-Hydroxy-3-Oxopentanoate is a versatile keto-ester compound that serves as a valuable building block in organic synthesis. This chemical matters for its bifunctional reactivity, featuring both a hydroxyl and a keto group, which allows for selective transformations and complex molecule construction. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), chiral intermediates, and complex natural products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of statin-class drugs and other therapeutic molecules.
• Chiral Synthesis: Used in asymmetric synthesis to construct stereogenic centers for optically active compounds.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and advanced material monomers.
• Biochemical Research: Employed in the study of metabolic pathways and enzyme inhibition as a substrate analog.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers with tailored properties.
• Agrochemical Synthesis: Utilized in the development of advanced pesticides and herbicides.

Basic Information

Product Name	Ethyl 5-Hydroxy-3-Oxopentanoate
CAS No.	64714-85-8
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	5-Hydroxy-3-oxopentanoic acid ethyl ester; Ethyl 5-hydroxy-3-oxovalerate; 3-Oxopentanedioic acid 5-ethyl ester; Ethyl 3-keto-5-hydroxypentanoate; 3-Keto-5-hydroxypentanoic acid ethyl ester; Ethyl levulinate derivative; 5-Hydroxy-3-oxovaleric acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Hydroxy-3-Oxopentanoate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed after each use to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.