Description

Flavokawain A CAS NO 64680-84-8 is a naturally occurring chalcone derivative, a key bioactive constituent found in the kava plant (*Piper methysticum*). This compound is of significant commercial and research interest due to its potent biological activities, including anti-inflammatory, antioxidant, and notable anti-proliferative properties against various cell lines. It is primarily sought after by manufacturers and researchers in the pharmaceutical, nutraceutical, and life science research sectors for drug discovery, formulation development, and as a high-purity reference standard.

Application

• Pharmaceutical Research & Development: As a lead compound or reference standard in studies targeting cancer, inflammation, and neurological disorders.
• Nutraceutical Formulation: Incorporated into dietary supplements for its potential antioxidant and wellness-supporting benefits.
• Biochemical Research: Used in cell-based assays and mechanistic studies to investigate apoptosis, cell cycle arrest, and signaling pathways.
• Reference Standard: Serves as a high-purity calibrant for analytical methods (HPLC, LC-MS) in quality control laboratories.
• Cosmeceutical Ingredients: Explored for use in skincare formulations for its anti-inflammatory and protective properties.

Basic Information

Product Name	Flavokawain A
CAS No.	64680-84-8
Molecular Formula	C₁₆H₁₄O₄
Molecular Weight	270.28 g/mol
Synonyms	Flavokawain A; (E)-1-(2'-Hydroxy-4',6'-dimethoxyphenyl)-3-phenyl-2-propen-1-one; 2',4'-Dimethoxy-6'-hydroxychalcone; Flavokavain A; FKA; Natural Chalcone K
EINECS	Contact for details

Quality Control

Our Flavokawain A is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms for purity verification. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is available for every batch upon request, supporting compliance in research and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.