Description

Piperidin-4-Yl-(3-Trifluoromethyl-Phenyl)-Methanone Hydrochloride is a high-purity, pharmaceutically relevant chemical intermediate. This compound is valued for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique trifluoromethylphenyl moiety.
• Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules in medicinal and process chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for method development and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	Piperidin-4-Yl-(3-Trifluoromethyl-Phenyl)-Methanone Hydrochloride
CAS No.	64670-97-9
Molecular Formula	C13H14F3NO•HCl
Molecular Weight	281.71 g/mol (Free base: 245.25 g/mol)
Synonyms	1-(3-(Trifluoromethyl)benzoyl)piperidin-4-amine hydrochloride; 4-Amino-1-[3-(trifluoromethyl)benzoyl]piperidine hydrochloride; 4-Amino-1-(3-trifluoromethylbenzoyl)piperidine HCl; (3-Trifluoromethylphenyl)(4-piperidinyl)methanone hydrochloride; 4-Piperidinamine, 1-[3-(trifluoromethyl)benzoyl]-, hydrochloride; 64670-97-9 (CAS)
EINECS	Contact for details

Quality Control

Our Piperidin-4-Yl-(3-Trifluoromethyl-Phenyl)-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and residual solvents. Our quality standards are designed to meet the stringent requirements of pharmaceutical development and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.