Description

Tms Dl-Serine CAS NO 64625-17-8 is a protected derivative of the amino acid serine, where the hydroxyl group is functionalized with a trimethylsilyl (TMS) group. This modification is critical for enhancing the molecule's stability and solubility in organic solvents, making it a valuable synthetic intermediate. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for advanced organic synthesis, particularly in peptide chemistry and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and peptide-based therapeutics.
• Peptide Synthesis: Used as a protected serine derivative in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Chemical Research: Essential reagent in academic and industrial R&D for exploring new synthetic pathways and creating specialized chemical libraries.
• Fine Chemical Production: Intermediate in the manufacture of high-value specialty chemicals, including chiral auxiliaries and catalysts.
• Bioconjugation: Serves as a modified amino acid for creating chemically defined protein conjugates and probes.

Basic Information

Product Name	Tms Dl-Serine
CAS No.	64625-17-8
Molecular Formula	C6H15NO3Si
Molecular Weight	177.28 g/mol
Synonyms	O-Trimethylsilyl-DL-serine; DL-Serine O-trimethylsilyl ether; Trimethylsilyl-DL-serinate; Serine, O-(trimethylsilyl)-, DL-; TMS-Serine; TMS-DL-Ser; (RS)-2-Amino-3-[(trimethylsilyl)oxy]propanoic acid
EINECS	Contact for details

Quality Control

Our Tms Dl-Serine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.