Description

2-Chloro-5-(Pyrrolidin-1-Ylcarbonyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core functionalized with a pyrrolidine amide group. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is critical. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Serves as a key building block for developing advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research due to its potential as a nitrogen-donor ligand.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-5-(Pyrrolidin-1-Ylcarbonyl)Pyridine
CAS No.	64614-47-7
Molecular Formula	C11H11ClN2O
Molecular Weight	222.67 g/mol
Synonyms	2-Chloro-5-(1-pyrrolidinylcarbonyl)pyridine; 2-Chloro-5-pyrrolidin-1-ylcarbonylpyridine; 1-(6-Chloropyridin-3-yl)-2-pyrrolidin-1-ylethanone; 2-Chloro-5-(pyrrolidine-1-carbonyl)pyridine; 5-Chloro-2-(pyrrolidine-1-carbonyl)pyridine; 64614-47-7; Pyrrolidine, 1-[(6-chloro-3-pyridinyl)carbonyl]-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Pyrrolidin-1-Ylcarbonyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.