Description

Tms Dl-Threonine is a protected derivative of the amino acid threonine, where the hydroxyl group is silylated with a trimethylsilyl (TMS) group. This modification is crucial for enhancing the molecule's stability and solubility in organic solvents, making it a valuable synthetic intermediate. It is primarily sought after by researchers and manufacturers in the pharmaceutical and fine chemical industries for applications in peptide synthesis and the development of novel bioactive compounds.

Application

• Peptide Synthesis: Serves as a key protected building block in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Employed in studies involving amino acid metabolism, enzyme substrates, and the synthesis of labeled compounds.
• Fine Chemical Production: Acts as a specialized intermediate in the synthesis of complex organic molecules and chiral compounds.
• Protecting Group Chemistry: Demonstrates the utility of the TMS group for the temporary protection of alcohol functionalities in multi-step syntheses.

Basic Information

Product Name	Tms Dl-Threonine
CAS No.	64569-35-3
Molecular Formula	C7H17NO3Si
Molecular Weight	191.30 g/mol
Synonyms	DL-Threonine TMS derivative; O-Trimethylsilyl-DL-threonine; Threonine, O-(trimethylsilyl)-, DL-; Trimethylsilyl-DL-threonine; N-(Trimethylsilyl)threonine; DL-Threonine, O-(trimethylsilyl)-; (RS)-2-Amino-3-[(trimethylsilyl)oxy]butanoic acid; TMS-Thr-OH
EINECS	Contact for details

Quality Control

Our Tms Dl-Threonine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.