Description

Salafibrate is a synthetic organic compound belonging to the fibrate class of chemicals, known for its role as a pharmaceutical intermediate. This compound is crucial for the research and development of lipid-regulating agents, offering a key building block for advanced therapeutic synthesis. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on metabolic and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fibrate-based active pharmaceutical ingredients (APIs) for lipid management.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new peroxisome proliferator-activated receptor (PPAR) agonists.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Employed in metabolic pathway studies to investigate mechanisms of lipid metabolism and related disorders.

Basic Information

Product Name	Salafibrate
CAS No.	64496-66-8
Molecular Formula	C19H20O5
Molecular Weight	328.36 g/mol
Synonyms	Salafibrate; 2-[4-(1-Oxoisoindolin-2-yl)phenoxy]-2-methylpropanoic acid; 2-Methyl-2-[4-(1-oxoisoindolin-2-yl)phenoxy]propanoic acid; 2-[4-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)phenoxy]-2-methylpropanoic acid; Isoindolin-1-one derivative; Fibrate derivative; Lipid regulator intermediate.
EINECS	Contact for details

Quality Control

Our Salafibrate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.