Description

1-(4-Methoxybenzofuran-5-Yl)-3-Phenyl-2-Propen-1-One is a specialized organic compound belonging to the chalcone class, characterized by its benzofuran and propenone structural motifs. This compound is valued for its role as a versatile synthetic intermediate and a key scaffold in the development of novel bioactive molecules. It is primarily required by research institutions and pharmaceutical companies engaged in medicinal chemistry, organic synthesis, and the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Organic Synthesis: Acts as a precursor for the synthesis of more complex heterocyclic compounds, including flavonoids and other fused-ring systems.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor-ligand interactions due to its chalcone-based structure.
• Material Science Precursor: Investigated for use in the development of organic semiconductors and non-linear optical (NLO) materials.

Basic Information

Product Name	1-(4-Methoxybenzofuran-5-Yl)-3-Phenyl-2-Propen-1-One
CAS No.	64280-20-2
Molecular Formula	C18H14O3
Molecular Weight	278.30 g/mol
Synonyms	5-(3-Oxo-3-phenylpropenyl)-4-methoxybenzofuran; 3-Phenyl-1-(4-methoxy-5-benzofuranyl)-2-propen-1-one; 1-(4-Methoxy-5-benzofuranyl)-3-phenyl-2-propen-1-one; (E)-1-(4-Methoxybenzofuran-5-yl)-3-phenylprop-2-en-1-one; 4-Methoxy-5-benzofuranyl 3-phenyl-2-propenyl ketone; Chalcone derivative (4-methoxybenzofuran); Benzofuran chalcone
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxybenzofuran-5-Yl)-3-Phenyl-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.