Description

Acetic Acid 1-Methyl-6-Oxo-3-(Trimethylsilyl)-2,4-Cyclohexadienyl Ester is a specialized organosilicon intermediate featuring a unique cyclohexadienone core. This compound matters for its role as a versatile synthon in advanced organic synthesis, enabling the introduction of both silyl-protected functionalities and reactive ketone groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecular architectures, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Advanced Organic Synthesis: Serves as a versatile precursor for Diels-Alder reactions and other cycloadditions to construct polycyclic frameworks.
• Silicon-Containing Compound Research: Used in the development and study of new organosilicon molecules with potential applications in materials science.
• Fine Chemical Production: Employed in the manufacture of high-purity, low-volume specialty chemicals for research and industrial applications.
• Protecting Group Strategy: The trimethylsilyl (TMS) group can act as a temporary protecting group for alcohols or other functionalities during complex synthetic sequences.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical transformations in university and corporate research laboratories.

Basic Information

Product Name	Acetic Acid 1-Methyl-6-Oxo-3-(Trimethylsilyl)-2,4-Cyclohexadienyl Ester
CAS No.	64248-40-4
Molecular Formula	C12H20O3Si
Molecular Weight	240.37 g/mol
Synonyms	3-(Trimethylsilyl)-1-methyl-2,4-cyclohexadien-6-one-1-acetate; 1-Methyl-6-oxo-3-(trimethylsilyl)-2,4-cyclohexadien-1-yl acetate; 3-Trimethylsilyl-1-methyl-6-oxo-1,4-cyclohexadien-1-yl acetate; TMS-Cyclohexadienone Acetate; (1-Methyl-6-oxo-3-(trimethylsilyl)-2,4-cyclohexadienyl) acetate; 3-(Trimethylsilyl)-1-methyl-2,4-cyclohexadien-6-ol, 1-acetate; 1-Acetoxy-1-methyl-3-trimethylsilyl-2,4-cyclohexadien-6-one
EINECS	Contact for details

Quality Control

Our Acetic Acid 1-Methyl-6-Oxo-3-(Trimethylsilyl)-2,4-Cyclohexadienyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.