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n-Benzyloxycarbonyl-3-Phenyl-L-Alanine 1,2-Dibromoethyl Ester CAS NO 64187-43-5


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CAS No.:64187-43-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Benzyloxycarbonyl-3-Phenyl-L-Alanine 1,2-Dibromoethyl Ester is a specialized, high-purity protected amino acid derivative designed for advanced synthetic chemistry. This compound serves as a critical chiral building block, enabling the controlled synthesis of complex peptides and peptidomimetics with high stereochemical fidelity. It is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and fine chemical synthesis who require reliable, high-quality intermediates for constructing sophisticated molecular architectures.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of phenylalanine derivatives with orthogonal protecting groups.
  • Protease Inhibitor Development: Serves as a precursor in the design and synthesis of protease inhibitors and other enzyme-targeting drug candidates.
  • Agrochemical Research: Employed in the synthesis of bioactive peptides and amino acid analogs for crop protection and agricultural science applications.
  • Bioconjugation & Labeling: Useful in creating modified peptides for bioconjugation, diagnostic probe development, and biochemical labeling studies.
  • Academic & Institutional Research: A valuable reagent for universities and research institutes exploring new methodologies in organic and medicinal chemistry.

Basic Information

Item Details
Product Name n-Benzyloxycarbonyl-3-Phenyl-L-Alanine 1,2-Dibromoethyl Ester
CAS No. 64187-43-5
Molecular Formula C19H19Br2NO4
Molecular Weight 485.17 g/mol
Synonyms Z-3-Phenyl-L-Alanine 1,2-Dibromoethyl Ester; Cbz-3-Phe(1,2-Dibromoethyl); N-Carbobenzoxy-3-phenyl-L-alanine 1,2-dibromoethyl ester; Nα-Z-3-Phenylalanine 1,2-dibromoethyl ester; (S)-1,2-Dibromoethyl 2-((benzyloxy)carbonylamino)-3-phenylpropanoate; N-Benzyloxycarbonyl-L-3-phenylalanine 1,2-dibromoethyl ester; Z-Phe(1,2-Dibromoethyl)-OH; Protected 3-Phenylalanine dibromoethyl ester
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Quality Control

Our n-Benzyloxycarbonyl-3-Phenyl-L-Alanine 1,2-Dibromoethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full characterization data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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