Description

n-[(Benzyloxy)Carbonyl]Glycine Ethenyl Ester is a versatile N-protected amino acid derivative, specifically a Cbz-protected glycine vinyl ester, serving as a crucial building block in synthetic organic chemistry. Its primary value lies in enabling controlled peptide coupling and polymer synthesis through its reactive vinyl ester group, which offers distinct advantages over traditional alkyl esters in terms of reactivity and selectivity. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, facilitating the development of novel compounds and advanced materials.

Application

• Peptide Synthesis: Acts as a key monomer for introducing glycine residues in solid-phase and solution-phase peptide synthesis using the Cbz (carboxybenzyl) protecting group strategy.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Polymer Chemistry: Utilized in the preparation of functionalized polymers and polymeric materials via its polymerizable vinyl ester moiety.
• Agrochemical Research: Employed in the development and synthesis of novel herbicides, pesticides, and plant growth regulators.
• Bioconjugation: Used to create linkers and spacers for conjugating peptides to other molecules, such as dyes, drugs, or surfaces.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Material Science: Contributes to the synthesis of advanced organic materials with specific functional properties.

Basic Information

Product Name	n-[(Benzyloxy)Carbonyl]Glycine Ethenyl Ester
CAS No.	64187-24-2
Molecular Formula	C₁₂H₁₃NO₄
Molecular Weight	235.24 g/mol
Synonyms	N-Carbobenzoxyglycine Vinyl Ester; Cbz-Glycine Vinyl Ester; N-(Benzyloxycarbonyl)glycine Vinyl Ester; Z-Gly-OV; Vinyl N-Carbobenzoxyglycinate; Benzyl N-(Vinyloxycarbonylmethyl)carbamate; Glycine, N-[(phenylmethoxy)carbonyl]-, ethenyl ester; (Vinyloxycarbonylmethyl)carbamic acid benzyl ester
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]Glycine Ethenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.