Description

n-(p-Tolylsulfonyl)-L-Tyrosine Cyanomethyl Ester is a specialized, high-purity chemical building block used in advanced organic synthesis. This compound is valued for its role as a protected tyrosine derivative, enabling precise peptide and small molecule construction. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, proteomics, and the synthesis of novel bioactive compounds.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry Research: Used in the design and development of new drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Bioconjugation: Acts as a precursor for creating labeled peptides or protein conjugates for diagnostic and research applications.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes (ABPs) or photoaffinity labels for studying protein function.
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists in university and corporate research laboratories.

Basic Information

Product Name	n-(p-Tolylsulfonyl)-L-Tyrosine Cyanomethyl Ester
CAS No.	64187-18-4
Molecular Formula	C19H20N2O5S
Molecular Weight	388.44 g/mol
Synonyms	L-Tyrosine, N-[(4-methylphenyl)sulfonyl]-, cyanomethyl ester; N-Tosyl-L-tyrosine cyanomethyl ester; Tosyl-L-tyrosine cyanomethyl ester; N-(p-Toluenesulfonyl)-L-tyrosine cyanomethyl ester; N-Ts-L-Tyr-OCH2CN; (2S)-2-[[(4-Methylphenyl)sulfonyl]amino]-3-(4-hydroxyphenyl)propanoic acid cyanomethyl ester; Cyanomethyl N-tosyl-L-tyrosinate
EINECS	Contact for details

Quality Control

Our n-(p-Tolylsulfonyl)-L-Tyrosine Cyanomethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.