Description

Zapizolam is a high-purity benzodiazepine derivative with the CAS registry number 64098-32-4. This compound is valued for its specific pharmacological profile, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and analytical reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing.
• Biochemical Research: Employed in preclinical studies to investigate structure-activity relationships (SAR) and receptor binding affinity within the central nervous system.
• Metabolite Studies: Serves as a precursor or standard in the study of drug metabolism and pharmacokinetics (DMPK).

Basic Information

Product Name	Zapizolam
CAS No.	64098-32-4
Molecular Formula	C₁₉H₁₇ClN₄O₂
Molecular Weight	368.82 g/mol
Synonyms	Zapizolam; 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; CS-580; SH-582; Zapezolam; Zapazolam; Zapizolamum
EINECS	Contact for details

Quality Control

Our Zapizolam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.