Description

6-Bromo-3-Nitroimidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused-ring structure, bearing both bromo and nitro substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a critical precursor for coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides due to its bioactive heterocyclic core.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Nitro-Reduction Chemistry: The nitro group can be selectively reduced to an amine, enabling further derivatization for library synthesis in medicinal chemistry.

Basic Information

Product Name	6-Bromo-3-Nitroimidazo[1,2-A]Pyridine
CAS No.	64064-71-7
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	6-Bromo-3-nitroimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-bromo-3-nitro-; 3-Nitro-6-bromoimidazo[1,2-a]pyridine; 6-Bromo-3-nitro-imidazo[1,2-a]pyridine; 64064-71-7; 6-Br-3-NO2-Imidazopyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Nitroimidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.