Description

4-Chloropyridine-2-Carboxylic Acid Ethyl Ester is a versatile and high-purity organic building block essential for advanced chemical synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing pyridine-based molecular frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific chloropyridine motifs for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development projects.

Basic Information

Product Name	4-Chloropyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	64064-56-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Ethyl 4-Chloropicolinate; 4-Chloro-2-pyridinecarboxylic Acid Ethyl Ester; 4-Chloropicolinic Acid Ethyl Ester; 2-Carbethoxy-4-chloropyridine; Ethyl 4-Chloro-2-pyridinecarboxylate; 4-Chloro-2-(ethoxycarbonyl)pyridine; Picolinic acid, 4-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloropyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.