Description

4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Imino]-3,5-Dimethyl-2,5-Cyclohexadien-1-One is a specialized nitrogen mustard derivative quinone imine compound, primarily recognized for its role as a key synthetic intermediate in advanced pharmaceutical research. Its molecular structure, featuring a bis(chloroethyl)amino group, makes it a critical precursor for developing targeted therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly those focused on oncology drug discovery and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Anticancer Drug Research: Used in R&D for developing novel alkylating agents that target DNA replication in cancer cells.
• Bioconjugation Studies: Acts as a linker or payload in antibody-drug conjugate (ADC) research due to its reactive functional groups.
• Biochemical Probe Development: Utilized in creating probes to study enzyme inhibition and cellular signaling pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex heterocyclic compounds and specialty chemicals.
• Academic & Institutional Research: Supports chemical biology and medicinal chemistry programs in universities and research institutes.

Basic Information

Product Name	4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Imino]-3,5-Dimethyl-2,5-Cyclohexadien-1-One
CAS No.	64048-65-3
Molecular Formula	C19H20Cl2N2O
Molecular Weight	363.28 g/mol
Synonyms	4-[[4-[Bis(2-chloroethyl)amino]phenyl]imino]-2,5-dimethyl-2,5-cyclohexadien-1-one; 2,5-Cyclohexadien-1-one, 4-[[4-[bis(2-chloroethyl)amino]phenyl]imino]-3,5-dimethyl-; NSC 338947; Nitrogen Mustard Quinone Imine Derivative; Bis(2-chloroethyl)amino phenylimino dimethyl cyclohexadienone
EINECS	Contact for details

Quality Control

Every batch of 4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Imino]-3,5-Dimethyl-2,5-Cyclohexadien-1-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures material traceability and reliability for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.