Description

1-[2-(Aminocarbonyloxy)-3-Methoxypropyl]-5-Ethyl-5-Phenylbarbituric Acid is a specialized barbiturate derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or active pharmaceutical ingredient (API) precursor, valued for its precise molecular architecture. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of central nervous system (CNS) agents, sedative-hypnotics, and other therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs).
• CNS Drug Research: Used in preclinical and research stages for developing sedative, hypnotic, or anticonvulsant drug candidates.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize pharmacological profiles.
• Process Chemistry: Utilized in route scouting and scale-up optimization for complex organic syntheses.

Basic Information

Product Name	1-[2-(Aminocarbonyloxy)-3-Methoxypropyl]-5-Ethyl-5-Phenylbarbituric Acid
CAS No.	64038-13-7
Molecular Formula	C₁₉H₂₃N₃O₆
Molecular Weight	389.40 g/mol
Synonyms	5-Ethyl-5-phenyl-1-[2-(aminocarbonyloxy)-3-methoxypropyl]barbituric acid; 1-[2-(Carbamoyloxy)-3-methoxypropyl]-5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione; 5-Ethyl-1-(2-hydroxycarbamoyl-3-methoxypropyl)-5-phenylbarbituric acid; NSC 339539; Barbituric acid, 1-[2-(aminocarbonyloxy)-3-methoxypropyl]-5-ethyl-5-phenyl-
EINECS	Contact for details

Quality Control

Our 1-[2-(Aminocarbonyloxy)-3-Methoxypropyl]-5-Ethyl-5-Phenylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.