Description

1-[2-(Aminocarbonyloxy)-3-Isobutyloxypropyl]-5-Ethyl-5-Phenylbarbituric Acid is a specialized barbiturate derivative with a complex molecular structure designed for targeted pharmacological activity. This compound is valued for its potential as a key intermediate in the synthesis of advanced central nervous system (CNS) agents and other fine pharmaceuticals. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic entities, particularly in the areas of sedative-hypnotics and neuroactive drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry research for structure-activity relationship (SAR) studies to develop new CNS-targeting compounds.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Preclinical Studies: Utilized in the formulation of compounds for pharmacological and toxicological evaluation in early-stage drug discovery.

Basic Information

Product Name	1-[2-(Aminocarbonyloxy)-3-Isobutyloxypropyl]-5-Ethyl-5-Phenylbarbituric Acid
CAS No.	64038-11-5
Molecular Formula	C₂₁H₂₉N₃O₆
Molecular Weight	419.47 g/mol
Synonyms	5-Ethyl-5-phenyl-1-[2-(aminocarbonyloxy)-3-(2-methylpropoxy)propyl]barbituric acid; 1-[2-(Carbamoyloxy)-3-isobutoxypropyl]-5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione; 5-Ethyl-1-[2-(hydroxycarbamoyloxy)-3-isobutoxypropyl]-5-phenylbarbituric acid; Barbituric acid derivative (64038-11-5); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-[2-(Aminocarbonyloxy)-3-Isobutyloxypropyl]-5-Ethyl-5-Phenylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant pharmacopeial tests. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.