Description

4-Acetyl-4-Bromobutyric Acid Methyl Ester is a high-purity brominated ester building block of significant value in advanced organic synthesis. This compound is essential for the controlled introduction of both acetyl and bromo functional groups, enabling the construction of complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of complex drug candidates, particularly those requiring bromine atoms for further functionalization or as part of the final active pharmaceutical ingredient (API).
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its reactive bromine site allows for the creation of diverse chemical structures.
• Organic Synthesis Building Block: Serves as a versatile precursor in multi-step synthesis for creating lactones, heterocycles, and other specialized organic compounds in academic and industrial R&D settings.
• Material Science Research: Employed in the development of novel polymers or functional materials that incorporate ester and ketone functionalities.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.

Basic Information

Product Name	4-Acetyl-4-Bromobutyric Acid Methyl Ester
CAS No.	64037-74-7
Molecular Formula	C7H11BrO3
Molecular Weight	223.07 g/mol
Synonyms	Methyl 4-Acetyl-4-bromobutanoate; 4-Bromo-4-oxobutyl acetate methyl ester; 4-Bromo-4-oxo-butylacetic acid methyl ester; Butanoic acid, 4-acetyl-4-bromo-, methyl ester; Methyl 4-bromo-4-oxobutanoate (related); 4-Bromo-4-oxobutyric acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-Acetyl-4-Bromobutyric Acid Methyl Ester is produced and tested under stringent quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request for quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.