Description

7-Chloro-n-Methyl-5-Phenyl-n-(Phenylmethyl)-3H-1,4-Benzodiazepin-2-Amine4-Oxide is a specialized benzodiazepine derivative, a key chemical class in medicinal chemistry and pharmaceutical research. This compound matters as a crucial advanced pharmaceutical intermediate for the development of novel therapeutic agents, offering researchers a versatile building block with a complex, functionalized structure. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a key scaffold or building block for structure-activity relationship (SAR) studies and the discovery of new therapeutic compounds.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and impurity profiling.
• Process Chemistry Development: Utilized in optimizing synthetic routes and scaling up production processes for complex organic molecules.
• Biochemical Research: May be investigated for its interaction with biological targets such as GABA receptors, given its benzodiazepine core structure.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, target-specific molecules for client-driven research projects.

Basic Information

Item	Detail
Product Name	7-Chloro-n-Methyl-5-Phenyl-n-(Phenylmethyl)-3H-1,4-Benzodiazepin-2-Amine4-Oxide
CAS No.	63991-69-5
Molecular Formula	C23H20ClN3O
Molecular Weight	389.88 g/mol
Synonyms	7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide; 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepine-2-amine 4-oxide; 7-Chloro-1-methyl-5-phenyl-1,4-benzodiazepin-2-amine 4-oxide; Ro 07-9749/000; Ro 07-9749; Ro 07-9749/001; 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine N-oxide
EINECS	Contact for details

Quality Control

Our 7-Chloro-n-Methyl-5-Phenyl-n-(Phenylmethyl)-3H-1,4-Benzodiazepin-2-Amine4-Oxide is produced under strict quality management protocols. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available for every batch. We adhere to cGMP principles where applicable to support our clients in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive compound from degradation and to prevent contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.