Description

n-5-Carbobenzoxy-5-Aminopentanoic Acid T-Butyl Ester is a protected amino acid derivative, specifically a Cbz-protected 5-aminopentanoic acid t-butyl ester, serving as a crucial building block in organic synthesis. Its primary value lies in providing orthogonal protection for the amine and carboxylic acid functional groups, enabling precise, sequential reactions in complex molecule assembly. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the synthesis of peptides, peptidomimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate modified or non-natural amino acid residues.
• Protease Inhibitor Development: Serves as a precursor in the design and synthesis of protease inhibitors due to its amino acid-like structure.
• Linker Molecule for Bioconjugation: The protected functional groups allow it to act as a spacer or linker in the conjugation of drugs to carriers like antibodies or polymers.
• Chemical Biology Research: Employed in the synthesis of chemical probes and tools for studying biological processes.
• Custom Synthesis Services: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis.

Basic Information

Product Name	n-5-Carbobenzoxy-5-Aminopentanoic Acid T-Butyl Ester
CAS No.	63983-88-0
Molecular Formula	C17H25NO4
Molecular Weight	307.39 g/mol
Synonyms	5-[(Benzyloxy)carbonyl]amino]pentanoic acid 1,1-dimethylethyl ester; N5-Cbz-5-aminopentanoic acid tert-butyl ester; tert-Butyl 5-[(benzyloxycarbonyl)amino]pentanoate; N-Carbobenzoxy-1,5-diaminopentane-5-carboxylic acid t-butyl ester; Boc-C5(Z)-OH (common abbreviation); Z-5-Amino-pentanoic acid t-butyl ester; Cbz-5-Aminopentanoic Acid O-t-Butyl Ester; 5-(Benzyloxycarbonylamino)pentanoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-5-Carbobenzoxy-5-Aminopentanoic Acid T-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.