Description

(2R,6R,7α,8β)-7-[(Z)-1-Buten-3-Ynyl]-2-(4-Pentynyl)-1-Azaspiro[5.5]Undecan-8-Ol is a complex, high-purity chiral organic compound featuring a unique spirocyclic and alkyne-functionalized structure. This compound is of significant interest in advanced organic synthesis and pharmaceutical research, serving as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs) and complex natural product analogs. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-fidelity chiral intermediates for cutting-edge R&D projects.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used in the synthesis of novel, biologically active molecules for crop protection and pest management studies.
• Chemical Biology Probe: Serves as a scaffold or precursor for creating molecular probes to study enzyme mechanisms and biological pathways due to its reactive alkyne groups.
• Asymmetric Catalysis Ligand Precursor: Potential use in the development of novel chiral ligands or organocatalysts for stereoselective synthesis.
• Material Science Research: Exploration as a monomer or cross-linker for advanced polymers with specialized optical or mechanical properties.
• Academic & Institutional R&D: A valuable compound for methodological studies in synthetic organic chemistry, particularly in spirocycle formation and alkyne chemistry.

Basic Information

Product Name	(2R,6R,7α,8β)-7-[(Z)-1-Buten-3-Ynyl]-2-(4-Pentynyl)-1-Azaspiro[5.5]Undecan-8-Ol
CAS No.	63983-63-1
Molecular Formula	C20H29NO
Molecular Weight	299.45 g/mol
Synonyms	1-Azaspiro[5.5]undecan-8-ol, 7-[(1Z)-1-buten-3-ynyl]-2-(4-pentynyl)-, (2R,6R,7α,8β)-; (2R,6R,7α,8β)-7-[(1Z)-1-Buten-3-yn-1-yl]-2-(4-pentyn-1-yl)-1-azaspiro[5.5]undecan-8-ol; (2R,6R,7α,8β)-7-[(Z)-1-Buten-3-ynyl]-2-(4-pentynyl)-1-azaspiro[5.5]undecan-8-ol; 1-Azaspiro[5.5]undecan-8-ol, 7-(1-butyn-3-enyl)-2-(4-pentynyl)-, (2R,6R,7α,8β)-; CAS 63983-63-1
EINECS	Contact for details

Quality Control

Our (2R,6R,7α,8β)-7-[(Z)-1-Buten-3-Ynyl]-2-(4-Pentynyl)-1-Azaspiro[5.5]Undecan-8-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.