Description

4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Amino]-2,6-Dimethylphenol is a specialized nitrogen mustard derivative with a phenolic core, designed for advanced chemical synthesis and research applications. This compound matters for its role as a key synthetic intermediate in the development of targeted bioactive molecules, offering a unique bifunctional structure for conjugation and derivatization. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists working on novel polymer cross-linking agents and targeted therapeutic platforms.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential anticancer agents and targeted drug conjugates, leveraging its nitrogen mustard moiety.
• Bioconjugation Research: Used in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its reactive chloroethyl groups and phenolic handle.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides and plant growth regulators requiring specific alkylating and phenolic properties.
• Polymer Chemistry: Acts as a cross-linking agent or monomer in the production of specialty resins and functional polymers.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme inhibition and cellular signaling pathways.
• Material Science Research: Investigated for creating novel organic frameworks and coatings with specific chemical functionalities.

Basic Information

Product Name	4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Amino]-2,6-Dimethylphenol
CAS No.	63979-56-6
Molecular Formula	C19H24Cl2N2O
Molecular Weight	367.31 g/mol
Synonyms	2,6-Dimethyl-4-[[4-[bis(2-chloroethyl)amino]phenyl]amino]phenol; Phenol, 4-[[4-[bis(2-chloroethyl)amino]phenyl]amino]-2,6-dimethyl-; 4-((4-(Bis(2-chloroethyl)amino)phenyl)amino)-2,6-dimethylphenol; Nitrogen Mustard Phenol Derivative; Chlorambucil Phenol Analog
EINECS	Contact for details

Quality Control

Our 4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Amino]-2,6-Dimethylphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and related substances. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.