Description

4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Amino]Phenol is a specialized organic compound featuring a phenol core substituted with a nitrogen mustard derivative, making it a key intermediate for advanced chemical synthesis. This compound matters for its role in the development of targeted pharmaceutical agents and high-performance materials, where its specific molecular architecture enables precise functionalization. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in creating novel therapeutic compounds, particularly in oncology research, and specialized polymer chemistry.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted drug candidates.
• Anticancer Research: Used in academic and industrial R&D for developing novel alkylating agents and studying their mechanisms of action.
• Bioconjugation Chemistry: Serves as a linker or functional handle for attaching cytotoxic payloads to antibodies, proteins, or other targeting molecules in ADC (Antibody-Drug Conjugate) development.
• Polymer Modification: Employed to introduce reactive amine and phenol groups into polymer backbones for creating functional resins or specialty coatings.
• Dye and Pigment Synthesis: Intermediate in the production of complex aromatic dyes and high-stability pigments.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme activity and cellular pathways.

Basic Information

Product Name	4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Amino]Phenol
CAS No.	63979-55-5
Molecular Formula	C16H18Cl2N2O
Molecular Weight	325.23 g/mol
Synonyms	4-[4-[Bis(2-chloroethyl)amino]anilino]phenol; Phenol, 4-[[4-[bis(2-chloroethyl)amino]phenyl]amino]-; 4-((4-(Bis(2-chloroethyl)amino)phenyl)amino)phenol; Nitrogen Mustard Phenol Derivative; Chlorambucil Intermediate Analog; 2-Chloro-N-(2-chloroethyl)-N-[4-(4-hydroxyphenyl)amino]phenyl]ethanamine
EINECS	Contact for details

Quality Control

Our 4-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Amino]Phenol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.