Description

n-[4-[Bis(2-Chloroethyl)Amino]Phenyl]-4-Hydroxy-1-Naphthalenamine is a specialized nitrogen mustard derivative, a class of compounds known for their alkylating properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It serves as a critical intermediate for researchers and manufacturers in the life sciences sector, enabling the development of novel drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Used as a reference standard or active compound in studies investigating alkylating mechanisms, DNA interaction, and cytotoxicity.
• Antineoplastic Agent Development: Serves as a core structural moiety for developing new candidates in oncology drug discovery programs.
• Academic & Contract Research: Employed in university and CRO laboratories for mechanistic studies and the preparation of specialized chemical libraries.

Basic Information

Product Name	n-[4-[Bis(2-Chloroethyl)Amino]Phenyl]-4-Hydroxy-1-Naphthalenamine
CAS No.	63978-92-7
Molecular Formula	C20H20Cl2N2O
Molecular Weight	375.29 g/mol
Synonyms	4-Hydroxy-1-naphthalenamine, N-[4-[bis(2-chloroethyl)amino]phenyl]-; 1-Naphthalenamine, 4-hydroxy-N-[4-[bis(2-chloroethyl)amino]phenyl]-; 4-Hydroxy-N-[4-[bis(2-chloroethyl)amino]phenyl]-1-naphthylamine; Nitrogen mustard naphthylamine derivative; Chlorambucil naphthol analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-[4-[Bis(2-Chloroethyl)Amino]Phenyl]-4-Hydroxy-1-Naphthalenamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.