Description

1,2-Dihydroxypropyl 3-Hydroxy-3-Phenylalaninate is a specialized organic compound with a unique structure combining phenylalanine and glycerol moieties, making it a valuable intermediate in advanced synthesis. This compound matters for its role in creating complex molecules where precise chirality and functional group compatibility are critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used in academic and industrial R&D for creating peptide analogs and mimetics to study protein interactions.
• Chiral Synthesis: Serves as a chiral precursor or auxiliary in asymmetric synthesis for producing enantiomerically pure compounds.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, including advanced polymers, ligands for catalysis, and diagnostic reagents.
• Bioconjugation Chemistry: Potential use in developing linkers or spacers for antibody-drug conjugates (ADCs) or other bioconjugation platforms.

Basic Information

Product Name	1,2-Dihydroxypropyl 3-Hydroxy-3-Phenylalaninate
CAS No.	63978-27-8
Molecular Formula	C15H21NO6
Molecular Weight	311.33 g/mol
Synonyms	3-Hydroxy-3-phenylalanine 1,2-dihydroxypropyl ester; Glycerol 3-hydroxy-3-phenylalaninate; 3-Phenylserine glycerol ester; (2R,3S)-3-Hydroxy-3-phenylalanine 2,3-dihydroxypropyl ester (stereoisomer); 3-Hydroxy-3-phenylalanyl glycerol; α-Amino-β-hydroxyhydrocinnamic acid glycerol ester; DL-3-Phenylserine 1,2-dihydroxypropyl ester; Glycerol ester of 3-hydroxy-3-phenylalanine
EINECS	Contact for details

Quality Control

Our 1,2-Dihydroxypropyl 3-Hydroxy-3-Phenylalaninate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, IR) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (specify isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.