Description

Diethyl 2-Bromobenzylphosphonate is a high-purity organophosphorus compound, specifically a benzylphosphonate ester, serving as a versatile and critical synthetic intermediate. Its primary value lies in its role as a key building block for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient synthesis of alkenes and complex organic molecules. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable methods for constructing carbon-carbon double bonds.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing olefin-containing drug candidates and complex molecular scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific alkene functionalities.
• Material Science Research: Employed in the development of novel organic electronic materials, liquid crystals, and polymers where controlled alkene incorporation is necessary.
• Chemical Synthesis & Process Development: Acts as a stable phosphonate reagent in Horner-Wadsworth-Emmons (HWE) reactions for laboratories and pilot plants, offering advantages in yield and stereoselectivity.
• Fine Chemical Manufacturing: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances requiring specific alkene bonds.

Basic Information

Product Name	Diethyl 2-Bromobenzylphosphonate
CAS No.	63909-55-7
Molecular Formula	C11H16BrO3P
Molecular Weight	307.12 g/mol
Synonyms	Diethyl (2-Bromobenzyl)phosphonate; (2-Bromobenzyl)phosphonic Acid Diethyl Ester; Diethyl (o-Bromobenzyl)phosphonate; Phosphonic Acid, P-[(2-Bromophenyl)methyl]-, Diethyl Ester; Diethyl α-Bromo-o-tolylphosphonate; 2-Bromobenzylphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-Bromobenzylphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.