Description

1,2,3,4,6,7-Hexahydro-10-Chloro-1-Phenyl-8H-Pyrido[3,2,1-Jk][1,4]Benzodiazepin-7-Ol is a complex heterocyclic organic compound belonging to the benzodiazepine class, serving as a crucial advanced pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and for research into central nervous system (CNS) therapeutics. This high-purity intermediate is essential for pharmaceutical R&D laboratories and manufacturers specializing in the development of proprietary drug candidates and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the multi-step synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Research & Development: Serves as a key starting material or intermediate in medicinal chemistry for the discovery and optimization of new drug candidates targeting neurological pathways.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing organizations (CMOs) for producing high-value, complex organic molecules.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional laboratories for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	1,2,3,4,6,7-Hexahydro-10-Chloro-1-Phenyl-8H-Pyrido[3,2,1-Jk][1,4]Benzodiazepin-7-Ol
CAS No.	63906-24-1
Molecular Formula	C19H19ClN2O
Molecular Weight	326.82 g/mol
Synonyms	10-Chloro-1-phenyl-1,2,3,4,6,7-hexahydro-8H-pyrido[3,2,1-jk][1,4]benzodiazepin-7-ol; 7-Hydroxy-10-chloro-1-phenyl-1,2,3,4,6,7-hexahydro-8H-pyrido[3,2,1-jk][1,4]benzodiazepine; 10-Chloro-1-phenyl-8H-pyrido[3,2,1-jk][1,4]benzodiazepin-7-ol, hexahydro-; CAS 63906-24-1
EINECS	Contact for details

Quality Control

Our 1,2,3,4,6,7-Hexahydro-10-Chloro-1-Phenyl-8H-Pyrido[3,2,1-Jk][1,4]Benzodiazepin-7-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.