Description

4-[3-[Bis(2-Chloroethyl)Amino]-4-Methylphenylsulfonyl]Morpholine is a specialized nitrogen mustard derivative with a morpholine sulfonamide functional group, representing a high-value chemical intermediate. This compound matters for its role in the synthesis of targeted bioactive molecules, offering a unique structural motif for pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of potential anticancer agents, leveraging its nitrogen mustard moiety for alkylating activity.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the sulfonyl morpholine group can contribute to biological activity and selectivity.
• Bioconjugation & Probe Development: Serves as a reactive handle for attaching payloads in antibody-drug conjugate (ADC) research or for creating molecular probes.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic & Institutional Research: Utilized in university and government laboratories for studying structure-activity relationships (SAR) and novel reaction pathways.
• Material Science Precursor: Potential intermediate in the synthesis of functional polymers or dyes with specific electronic properties.

Basic Information

Product Name	4-[3-[Bis(2-Chloroethyl)Amino]-4-Methylphenylsulfonyl]Morpholine
CAS No.	63905-03-3
Molecular Formula	C15H22Cl2N2O3S
Molecular Weight	381.32 g/mol
Synonyms	N,N-Bis(2-chloroethyl)-4-methyl-3-(morpholin-4-ylsulfonyl)aniline; 3-[(Bis(2-chloroethyl)amino]-4-methylbenzenesulfonmorpholide; 4-Methyl-3-(morpholinosulfonyl)-N,N-bis(2-chloroethyl)aniline; Morpholine, 4-[3-[bis(2-chloroethyl)amino]-4-methylbenzenesulfonyl]-; Nitrogen mustard morpholine sulfonamide derivative
EINECS	Contact for details

Quality Control

Our 4-[3-[Bis(2-Chloroethyl)Amino]-4-Methylphenylsulfonyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.