Description

6,7-Didehydro-4,5α-Epoxy-17-Methylmorphinan-3-Ol is a high-purity, specialized morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical characterization of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of neuropharmacology and analgesic research.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for specialized opioid receptor ligands and related pharmacologically active compounds.
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) testing in HPLC, GC-MS, and other chromatographic systems to ensure product purity and identity.
• Biochemical Research: Employed in receptor binding assays and pharmacological studies to investigate structure-activity relationships (SAR) and metabolic pathways.
• Process Development & Scale-up: Serves as a benchmark material for optimizing synthetic routes and purification processes during the transition from laboratory to pilot and commercial-scale production.
• Impurity Profiling: Acts as a known impurity or degradation product standard for stability studies and regulatory filing documentation for related drug substances.

Basic Information

Product Name	6,7-Didehydro-4,5α-Epoxy-17-Methylmorphinan-3-Ol
CAS No.	63732-65-0
Molecular Formula	C₁₈H₂₁NO₂
Molecular Weight	283.37 g/mol
Synonyms	17-Methylmorphinan-3-ol, 4,5α-epoxy-6,7-didehydro-; 4,5α-Epoxy-6,7-didehydro-17-methylmorphinan-3-ol; 6,7-Didehydro-4,5α-epoxy-17-methylmorphinan-3-ol; Morphinan-3-ol, 6,7-didehydro-4,5α-epoxy-17-methyl-; A key derivative in the morphinan alkaloid series.
EINECS	Contact for details

Quality Control

Every batch of 6,7-Didehydro-4,5α-Epoxy-17-Methylmorphinan-3-Ol is manufactured under controlled conditions and subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific results for identity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.