Description

6-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fused pyrazolopyridine core.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed as a molecular scaffold or probe in the study of biological pathways and target identification.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	6-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	63725-52-0
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	1-Methyl-6-chloro-1H-pyrazolo[3,4-b]pyridine; 6-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 6-chloro-1-methyl-; 6-Chloro-1-methylpyrazolo[3,4-b]pyridine; 1-Methyl-6-chloropyrazolo[3,4-b]pyridine; Pyrazolo[3,4-b]pyridine, 6-chloro-1-methyl-; 63725-52-0 (CAS)
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed HPLC/GC and NMR data are provided to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should minimize prolonged exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.