Description

Pyridine, 4-Methoxy-2-[(Trimethylsilyl)Oxy]- (9Ci) is a specialized organosilicon-protected pyridine derivative, serving as a key synthetic intermediate in advanced organic synthesis. Its value lies in the trimethylsilyl (TMS) protecting group, which enhances stability and directs reactivity for precise chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to construct complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing complex pyridine or pyrimidine cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific heterocyclic structures for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Organic Synthesis Reagent: Employed in multi-step synthesis as a protected hydroxyl-pyridine derivative for regioselective functionalization and cross-coupling reactions.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis and asymmetric synthesis.

Basic Information

Product Name	Pyridine, 4-Methoxy-2-[(Trimethylsilyl)Oxy]- (9Ci)
CAS No.	63676-48-2
Molecular Formula	C9H15NO2Si
Molecular Weight	197.31 g/mol
Synonyms	2-[(Trimethylsilyl)oxy]-4-methoxypyridine; 4-Methoxy-2-(trimethylsiloxy)pyridine; 4-Methoxy-2-pyridinol trimethylsilyl ether; 2-(Trimethylsiloxy)-4-methoxypyridine; 4-Methoxypyridin-2-yloxytrimethylsilane; TMS-protected 4-methoxy-2-hydroxypyridine; 4-Methoxy-2-(trimethylsilyloxy)pyridine; 2-(Trimethylsilyloxy)-4-methoxypyridine
EINECS	Contact for details

Quality Control

Our production of Pyridine, 4-Methoxy-2-[(Trimethylsilyl)Oxy]- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by modern analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.