Description

Dimethyl 3,5-Pyridinedicarboxylate n-Oxide is a high-purity, functionalized pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its unique N-oxide functionality and symmetrical dicarboxylate ester groups, which enable precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing functionalized pyridine cores for neurological and anti-infective applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine N-oxide moiety contributes to biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional polymers due to its rigid, symmetrical structure.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies aimed at discovering new bioactive compounds.

Basic Information

Item	Detail
Product Name	Dimethyl 3,5-Pyridinedicarboxylate n-Oxide
CAS No.	63667-40-3
Molecular Formula	C9H9NO5
Molecular Weight	211.17 g/mol
Synonyms	3,5-Pyridinedicarboxylic acid, dimethyl ester, N-oxide; Dimethyl 3,5-pyridinedicarboxylate 1-oxide; Dimethyl 3,5-pyridinedicarboxylate N-oxide; 3,5-Bis(methoxycarbonyl)pyridine N-oxide; Pyridine-3,5-dicarboxylic acid dimethyl ester N-oxide; 1-Oxidopyridine-3,5-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Every batch of Dimethyl 3,5-Pyridinedicarboxylate n-Oxide is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.