Description

(Z)-Methyl 2-(tert-Butoxycarbonylamino)But-2-Enoate is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and bioactive molecules.
• Peptide Chemistry: Used for the controlled incorporation of dehydroamino acid residues into peptide chains, modifying their structure and biological activity.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a versatile scaffold for analog development.
• Asymmetric Synthesis: Acts as a precursor for catalysts or ligands used in enantioselective transformations.
• Chemical Biology Probes: Utilized in the synthesis of labeled or modified amino acids for studying biological processes.
• Agrochemical Synthesis: Potential intermediate in the development of novel, chiral active ingredients for crop protection.

Basic Information

Product Name	(Z)-Methyl 2-(tert-Butoxycarbonylamino)But-2-Enoate
CAS No.	63658-16-2
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	Methyl (2Z)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-butenoate; Methyl (Z)-2-[(tert-Butoxycarbonyl)amino]but-2-enoate; Boc-DEHA-OMe; (Z)-Methyl 2-(Boc-amino)but-2-enoate; (Z)-2-(tert-Butoxycarbonylamino)-2-butenoic acid methyl ester; Methyl (Z)-2-(Boc-amino)crotonate; (Z)-Boc-δAbu-OMe; Methyl (Z)-2-[(tert-butoxycarbonyl)amino]crotonate
EINECS	Contact for details

Quality Control

Our (Z)-Methyl 2-(tert-Butoxycarbonylamino)But-2-Enoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (Z-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.