Description

Ethyl 5-Iodopyridine-3-Carboxylate is a high-value iodinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an ester and an iodine substituent, makes it a versatile intermediate for constructing complex heterocyclic systems and functionalized molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	Ethyl 5-Iodopyridine-3-Carboxylate
CAS No.	63473-00-7
Molecular Formula	C8H8INO2
Molecular Weight	277.06 g/mol
Synonyms	5-Iodonicotinic Acid Ethyl Ester; Ethyl 5-Iodo-3-pyridinecarboxylate; 3-Pyridinecarboxylic acid, 5-iodo-, ethyl ester; 5-Iodo-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-iodonicotinate; 5-Iodopyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Iodopyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.