Description

Atorvastatin CAS NO 63423-96-1 is a synthetic lipid-lowering agent belonging to the statin class of pharmaceuticals. It is a critical active pharmaceutical ingredient (API) valued for its potent inhibition of HMG-CoA reductase, a key enzyme in the cholesterol biosynthesis pathway. This high-purity compound is essential for pharmaceutical manufacturers and research institutions developing and producing medications to manage hypercholesterolemia and reduce cardiovascular risk.

Application

• Primary use as the Active Pharmaceutical Ingredient (API) in the manufacture of cholesterol-lowering tablets and other oral dosage forms.
• Formulation of generic and branded atorvastatin calcium medications for the treatment of dyslipidemia.
• Research and development of novel cardiovascular drug combinations and delivery systems.
• Use as a certified reference standard in analytical laboratories for quality control and method validation.
• Preclinical and clinical pharmacological studies investigating lipid metabolism.
• Production of combination drugs where atorvastatin is paired with other therapeutic agents like amlodipine.

Basic Information

Product Name	Atorvastatin
CAS No.	63423-96-1
Molecular Formula	C33H35FN2O5
Molecular Weight	558.64 g/mol
Synonyms	Atorvastatin Calcium Salt Precursor; (3R,5R)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic Acid; CI-981; Lipitor API; Atorvastatin Free Acid; SQ 33,600
EINECS	Contact for details

Quality Control

Our Atorvastatin is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and support with regulatory documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.