Description

1-(2,3,5-Tri-o-Acetyl--D-Ribofuranosyl)-4,6-Dichloroimidazo[4,5-C]Pyridine is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer agents, particularly those targeting nucleic acid synthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified nucleosides and nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of novel therapeutic agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA metabolism in cancer cells.
• Biochemical Tool Compound: Employed in enzymatic studies to investigate substrate specificity and inhibition of nucleoside-processing enzymes.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for the production of high-value, complex molecular entities.

Basic Information

Product Name	1-(2,3,5-Tri-o-Acetyl--D-Ribofuranosyl)-4,6-Dichloroimidazo[4,5-C]Pyridine
CAS No.	63423-94-9
Molecular Formula	C17H16Cl2N4O7
Molecular Weight	459.24 g/mol
Synonyms	4,6-Dichloro-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)imidazo[4,5-c]pyridine; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-4,6-dichloro-1H-imidazo[4,5-c]pyridine; 4,6-Dichloroimidazo[4,5-c]pyridine-1-β-D-ribofuranoside 2',3',5'-triacetate; Nucleoside analog intermediate; Acetylated ribofuranosyl dichloroimidazopyridine; CAS 63423-94-9
EINECS	Contact for details

Quality Control

Our production of 1-(2,3,5-Tri-o-Acetyl--D-Ribofuranosyl)-4,6-Dichloroimidazo[4,5-C]Pyridine adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. All batches undergo comprehensive analytical characterization including HPLC for purity assessment, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing lot-specific results are provided with every shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.