Description

Cyclopentanecarboxylic Acid, 2,3-Dihydroxy-, Methyl Ester, (1-α-,2-α-,3-α-)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique cyclopentane scaffold bearing vicinal diol and ester functionalities makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical development teams for applications in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

This specialized chiral synthon serves as a critical intermediate in several high-value chemical sectors:

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Utilized as a chiral precursor or auxiliary in stereoselective reactions to introduce defined stereocenters.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of novel bioactive molecules.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Used in methodological development and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2,3-Dihydroxy-, Methyl Ester, (1-α-,2-α-,3-α-)- (9Ci)
CAS No.	63358-33-8
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	(1α,2α,3α)-2,3-Dihydroxycyclopentanecarboxylic Acid Methyl Ester; Methyl (1α,2α,3α)-2,3-Dihydroxycyclopentanecarboxylate; (1R,2R,3R)-2,3-Dihydroxycyclopentanecarboxylic Acid Methyl Ester; Methyl (1R,2R,3R)-2,3-Dihydroxycyclopentanecarboxylate; cis,cis-2,3-Dihydroxycyclopentanecarboxylic Acid Methyl Ester; Cyclopentanecarboxylic acid, 2,3-dihydroxy-, methyl ester, (1R,2R,3R)-
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, chiral GC, NMR, and specific optical rotation measurement. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess, and other critical parameters to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.