Description

[R,(+)]-4-Hydroxyhexanoic Acid Lactone is a chiral lactone of significant interest in fine chemical synthesis. This compound serves as a versatile and valuable chiral building block for the production of pharmaceuticals and advanced materials. It is particularly essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Ingredient: Acts as a precursor for lactone-based flavor compounds, contributing to creamy, fruity, or coconut-like notes.
• Polymer Chemistry: Employed as a monomer or co-monomer in the synthesis of biodegradable polymers and specialty polyesters.
• Asymmetric Catalysis Research: Serves as a standard or substrate in the development and testing of new chiral catalysts and methodologies.
• Organic Synthesis Building Block: Utilized in various organic transformations, including ring-opening reactions and nucleophilic additions, to construct complex molecular architectures.

Basic Information

Product Name	[R,(+)]-4-Hydroxyhexanoic Acid Lactone
CAS No.	63357-95-9
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(R)-(+)-δ-Hexalactone; (R)-4-Hydroxyhexanoic Acid Lactone; (R)-5,6-Dihydro-6-methyl-2H-pyran-2-one; (R)-6-Methyl-5,6-dihydro-2H-pyran-2-one; (R)-Hexanolide; (R)-δ-Hexalactone; (R)-δ-Methyl-δ-valerolactone; D-(+)-δ-Hexalactone
EINECS	Contact for details

Quality Control

Our [R,(+)]-4-Hydroxyhexanoic Acid Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]20/D	+30° to +35° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.