Description

Lobenzarit is a synthetic disease-modifying antirheumatic drug (DMARD) with immunomodulatory properties. Its primary value lies in its ability to modulate immune responses, making it a compound of significant interest for pharmaceutical research and development. This product is essential for researchers and manufacturers in the pharmaceutical industry focusing on autoimmune and inflammatory conditions, as well as for use as a high-purity reference standard in analytical laboratories.

Application

• Pharmaceutical Active Ingredient (API): Core component in the research and development of novel therapeutics for autoimmune diseases like rheumatoid arthritis.
• Reference Standard: High-purity material used for quality control, method validation, and calibration in analytical testing (HPLC, GC-MS).
• Biochemical Research: Tool compound for studying immunomodulation pathways, T-cell function, and cytokine regulation in preclinical studies.
• Formulation Development: Used in R&D for creating various dosage forms, including tablets and capsules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials or niche pharmaceuticals.

Basic Information

Product Name	Lobenzarit
CAS No.	63329-53-3
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	2-[(2-Carboxyphenyl)amino]-4-quinazolinecarboxylic acid; CCA; Lobenzarit disodium; Carfenil; 4-Carboxy-2-(2-carboxyanilino)quinazoline; N-(2-Carboxyphenyl)-4-quinazolinecarboxylic-2-amine; NSC-356647; ONO-4601
EINECS	Contact for details

Quality Control

Our Lobenzarit is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is suitable for pharmaceutical research applications, with quality assurance protocols aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.