Description

Nicotinamidine Hydrochloride is a high-purity organic salt compound of significant interest in advanced chemical synthesis. This versatile intermediate is valued for its role in constructing complex heterocyclic structures, particularly within the pharmaceutical and agrochemical sectors. It serves as a critical building block for researchers and manufacturers developing novel active ingredients, offering a reliable pathway to introduce specific functional groups. Its consistent quality and stability are essential for ensuring reproducible results in demanding R&D and production environments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various nitrogen-containing heterocycles, potentially for antiviral, antibacterial, or central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its structural motif can contribute to biological activity.
• Chemical Research & Development: Employed as a versatile reagent in organic synthesis for constructing complex molecules, particularly in medicinal chemistry and material science projects.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in coordination chemistry and catalytic processes.
• Fine Chemical Production: Integral to the multi-step synthesis of other high-value, specialized fine chemicals and advanced intermediates.

Basic Information

Item	Detail
Product Name	Nicotinamidine Hydrochloride
CAS No.	63265-42-9
Molecular Formula	C6H8N3Cl
Molecular Weight	157.60 g/mol
Synonyms	3-Pyridinecarboximidamide hydrochloride; Nicotinimidamide hydrochloride; 3-Amidinopyridine hydrochloride; Pyridine-3-carboximidamide hydrochloride; 3-Cyanopyridine amidine hydrochloride; Nicotinamidine HCl; 3-Pyridylamidine hydrochloride
EINECS	Contact for details

Quality Control

Our Nicotinamidine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters such as assay (HPLC), impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.