Description

Ethyl (4-Iodobenzoyl)Acetate is a versatile and high-purity organic building block, specifically an iodinated aromatic β-ketoester. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, offering a reactive handle for further functionalization via the iodine atom and the active methylene group. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing iodinated aromatic or heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and photoactive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for biochemical and diagnostic applications.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	Ethyl (4-Iodobenzoyl)Acetate
CAS No.	63131-30-6
Molecular Formula	C11H11IO3
Molecular Weight	318.11 g/mol
Synonyms	4-Iodobenzoylacetic Acid Ethyl Ester; Ethyl 4-Iodobenzoylacetate; Ethyl (p-Iodobenzoyl)acetate; Acetic acid, 2-(4-iodobenzoyl)-, ethyl ester; 2-(4-Iodobenzoyl)acetic acid ethyl ester; 1-(4-Iodophenyl)-1,3-butanedione ethyl enol ether; Ethyl 3-oxo-3-(4-iodophenyl)propanoate
EINECS	Contact for details

Quality Control

Our Ethyl (4-Iodobenzoyl)Acetate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical testing including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.