Description

Estradiol-3-Benzoate-17-Butyrate is a synthetic, lipophilic ester derivative of the natural hormone estradiol, designed for enhanced stability and controlled release. This compound is critical for applications requiring a sustained estrogenic effect with improved pharmacokinetic profiles. It is primarily utilized by pharmaceutical R&D teams and manufacturers in the development of advanced hormone replacement therapies (HRT), veterinary medicines, and as a key reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of long-acting estrogenic prodrugs and combination hormonal therapies.
• Hormone Replacement Therapy (HRT) Research: Used in preclinical and formulation studies for developing sustained-release injectable or implantable delivery systems.
• Veterinary Pharmaceuticals: Employed in the formulation of estrus synchronization agents and growth-promoting implants for livestock.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Biochemical Research: Utilized in studies investigating estrogen receptor binding, metabolism, and the structure-activity relationships of steroid esters.

Basic Information

Product Name	Estradiol-3-Benzoate-17-Butyrate
CAS No.	63042-18-2
Molecular Formula	C29H36O4
Molecular Weight	448.60 g/mol
Synonyms	Estradiol 3-Benzoat 17-Butyrat; Estradiol 3-Benzoate 17-Butyrate; 17β-Estradiol 3-benzoat 17-butirat; Oestradiol-3-benzoate-17-butyrate; Estr-1,3,5(10)-triene-3,17β-diol 3-benzoat 17-butirat; NSC 17591; 3-Benzoyloxy-17β-butyryloxyestra-1,3,5(10)-triene
EINECS	Contact for details

Quality Control

Our Estradiol-3-Benzoate-17-Butyrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.